Can AMD Instinct MI325X run Llama 3.1 405B?

Yes, the AMD Instinct MI325X has 256GB VRAM and Llama 3.1 405B requires approximately 222.8GB VRAM for Q4 quantization. Estimated inference speed: 22 tokens/second.

✅ — AMD Instinct MI325X Can Run Llama 3.1 405B

The AMD Instinct MI325X packs 256GB VRAM. Llama 3.1 405B needs ~222.8GB. You're good to go.

✅ Plenty of headroom

AMD Instinct MI325X can run it — buy or rent

If you don't own this GPU yet, check retail prices or rent cloud capacity for a trial run.

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Hardware Specs

GPU: AMD Instinct MI325X
VRAM: 256 GB
Bandwidth: 6000 GB/s
MSRP: $25,000

Model Requirements

Model: Llama 3.1 405B
Parameters: 405B
VRAM (Q4): ~222.8 GB
Context: 128,000

Estimated Performance

22 tok/s

Estimated inference speed (Q4 quantization)

Run it locally with Ollama

ollama run llama3.1:405b

Requires Ollama installed on your machine

View on Ollama

Pricing

MSRP: $25,000

Llama 3.1 405B Details AMD Instinct MI325X Specs

Try Llama 3.1 405B on a different GPU

Try another model on AMD Instinct MI325X

Full compatibility matrix

HardwareHQ

✅ — AMD Instinct MI325X Can Run Llama 3.1 405B

The AMD Instinct MI325X packs 256GB VRAM. Llama 3.1 405B needs ~222.8GB. You're good to go.

✅ Plenty of headroom

AMD Instinct MI325X can run it — buy or rent

If you don't own this GPU yet, check retail prices or rent cloud capacity for a trial run.

Amazon eBay Compare cloud prices

We may earn a commission from cloud and hardware partners at no extra cost to you.

Hardware Specs

GPU: AMD Instinct MI325X
VRAM: 256 GB
Bandwidth: 6000 GB/s
MSRP: $25,000

Model Requirements

Model: Llama 3.1 405B
Parameters: 405B
VRAM (Q4): ~222.8 GB
Context: 128,000

Estimated Performance

22 tok/s

Estimated inference speed (Q4 quantization)

Run it locally with Ollama

ollama run llama3.1:405b

Requires Ollama installed on your machine

View on Ollama

Pricing

MSRP: $25,000

Llama 3.1 405B Details AMD Instinct MI325X Specs

Try Llama 3.1 405B on a different GPU

Try another model on AMD Instinct MI325X

Full compatibility matrix

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✅ — AMD Instinct MI325X Can Run Llama 3.1 405B

AMD Instinct MI325X can run it — buy or rent

Hardware Specs

Model Requirements

Estimated Performance

Run it locally with Ollama

Pricing

Try Llama 3.1 405B on a different GPU

Try another model on AMD Instinct MI325X

Related Checks

VRAM Calculator

Cloud GPU Pricing

GPU Comparison

Compatibility Lab

✅ — AMD Instinct MI325X Can Run Llama 3.1 405B

AMD Instinct MI325X can run it — buy or rent

Hardware Specs

Model Requirements

Estimated Performance

Run it locally with Ollama

Pricing

Try Llama 3.1 405B on a different GPU

Try another model on AMD Instinct MI325X

Related Checks

VRAM Calculator

Cloud GPU Pricing

GPU Comparison

Compatibility Lab