Can Radeon Instinct MI300A run gpt-oss 20B?

Yes, the Radeon Instinct MI300A has 192GB VRAM and gpt-oss 20B requires approximately 12.8GB VRAM for Q4 quantization. Estimated inference speed: 736 tokens/second.

✅ — Radeon Instinct MI300A Can Run gpt-oss 20B

The Radeon Instinct MI300A packs 192GB VRAM. gpt-oss 20B needs ~12.8GB (estimate). You're good to go.

Estimate · Q4_K_M · 4k context · batch 1. For dense 7B–70B this sits ~5–8% above the Q4_K_M GGUF file. Not peak runtime VRAM and not a measured bench.

✅ Plenty of headroom

Radeon Instinct MI300A can run it — buy or rent

If you don't own this GPU yet, check retail prices or rent cloud capacity for a trial run.

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Hardware Specs

GPU: Radeon Instinct MI300A
VRAM: 192 GB
Bandwidth: 10300 GB/s
MSRP: $17,000

Model Requirements

Model: gpt-oss 20B
Parameters: 21B total / 3.6B active · load estimate uses total
VRAM (Q4 estimate): ~12.8 GB
Context (estimate default): 4k

Estimated Performance

736 tok/s

Estimated inference speed (Q4 quantization) — bandwidth rule of thumb, not a measured bench

Run it locally with Ollama

ollama run gpt-oss:20b

Requires Ollama installed on your machine

View on Ollama

Pricing

MSRP: $17,000

gpt-oss 20B Details Radeon Instinct MI300A Specs

Try gpt-oss 20B on a different GPU

Try another model on Radeon Instinct MI300A

Full compatibility matrix

HardwareHQ

✅ — Radeon Instinct MI300A Can Run gpt-oss 20B

The Radeon Instinct MI300A packs 192GB VRAM. gpt-oss 20B needs ~12.8GB (estimate). You're good to go.

Estimate · Q4_K_M · 4k context · batch 1. For dense 7B–70B this sits ~5–8% above the Q4_K_M GGUF file. Not peak runtime VRAM and not a measured bench.

✅ Plenty of headroom

Radeon Instinct MI300A can run it — buy or rent

If you don't own this GPU yet, check retail prices or rent cloud capacity for a trial run.

Amazon eBay Compare cloud prices

We may earn a commission from cloud and hardware partners at no extra cost to you.

Hardware Specs

GPU: Radeon Instinct MI300A
VRAM: 192 GB
Bandwidth: 10300 GB/s
MSRP: $17,000

Model Requirements

Model: gpt-oss 20B
Parameters: 21B total / 3.6B active · load estimate uses total
VRAM (Q4 estimate): ~12.8 GB
Context (estimate default): 4k

Estimated Performance

736 tok/s

Estimated inference speed (Q4 quantization) — bandwidth rule of thumb, not a measured bench

Run it locally with Ollama

ollama run gpt-oss:20b

Requires Ollama installed on your machine

View on Ollama

Pricing

MSRP: $17,000

gpt-oss 20B Details Radeon Instinct MI300A Specs

Try gpt-oss 20B on a different GPU

Try another model on Radeon Instinct MI300A

Full compatibility matrix

Explore more

✅ — Radeon Instinct MI300A Can Run gpt-oss 20B

Radeon Instinct MI300A can run it — buy or rent

Hardware Specs

Model Requirements

Estimated Performance

Run it locally with Ollama

Pricing

Try gpt-oss 20B on a different GPU

Try another model on Radeon Instinct MI300A

Related Checks

VRAM Calculator

Cloud GPU Pricing

GPU Comparison

Compatibility Lab

✅ — Radeon Instinct MI300A Can Run gpt-oss 20B

Radeon Instinct MI300A can run it — buy or rent

Hardware Specs

Model Requirements

Estimated Performance

Run it locally with Ollama

Pricing

Try gpt-oss 20B on a different GPU

Try another model on Radeon Instinct MI300A

Related Checks

VRAM Calculator

Cloud GPU Pricing

GPU Comparison

Compatibility Lab