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✅ — AMD Instinct MI300A Can Run Claude Sonnet 4.5

The AMD Instinct MI300A packs 128GB VRAM. Claude Sonnet 4.5 needs ~66GB. You're good to go.

✅ Plenty of headroom

AMD Instinct MI300A can run it — buy or rent

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Hardware Specs

GPU
AMD Instinct MI300A
VRAM
128 GB
Bandwidth
4500 GB/s
MSRP
$17,000

Model Requirements

Model
Claude Sonnet 4.5
Parameters
120B
VRAM (Q4)
~66 GB
Context
200,000

Estimated Performance

56 tok/s
Estimated inference speed (Q4 quantization)

Pricing

MSRP: $17,000

Claude Sonnet 4.5 Details AMD Instinct MI300A Specs

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